Food Elimination Diet May Ease Migraine and IBS
Reuters Health Information, By Megan Brooks. Dec 13, 2012
NEW YORK (Reuters Health) Dec 13 - For patients with migraine and irritable bowel syndrome (IBS), an immunoglobulin G (IgG)-based food elimination diet may effectively reduce symptoms of both disorders, a small Turkish study suggests.
IgG antibodies against various food antigens have been linked to migraine; avoiding IgG-reactive foods has been shown to curb headache attacks. Dietary intolerance is also thought to be a significant contributor to IBS symptoms and there is some evidence that eliminating IgG-reactive foods may help calm IBS symptoms.
Because migraine and IBS often occur together, the Turkish team, led by Dr. Elif Ilgaz Aydinlar, from Acibaden University School of Medicine in Istanbul, evaluated the benefit of an IgG-based elimination diet in 21 patients with both migraine and uncomplicated IBS.
The double-blind, randomized, controlled, crossover study had three phases: baseline phase (usual diet, run-in); first diet phase (elimination or provocation diets, customized based on sensitivity results), and second diet phase (interchange of elimination or provocation diets).
In IgG antibody tests against 270 food allergens, the mean reaction count (abnormally high titer) was 23.1 mg/L. All values above 7.5 mg/L were considered as positive reaction to the corresponding food. Seeds and nuts and grains with gluten were the foods with the most frequent IgG positivity.